CDNA array technology in melanoma: An overview

被引：18

作者：

Baldi, A

Santini, D

De Luca, A

Paggi, MG

机构：

[1] Regina Elena Inst Canc Res, Ctr Expt Res, CRS, I-00158 Rome, Italy

[2] Univ Naples 2, Dept Biochem & Biophys F Cedrangolo, Sect Anat Pathol, Naples, Italy

[3] Serv Oncol, Rome, Italy

[4] Univ Naples 2, Dept Publ Hlth, Sect Clin Anat, Naples, Italy

来源：

JOURNAL OF CELLULAR PHYSIOLOGY | 2003年 / 196卷 / 02期

关键词：

D O I：

10.1002/jcp.10255

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Genetic aberrations, mostly resulting in changes in gene expression, are critical events in cancer onset and progression. The advent of the cDNA array technology allows the screening and the efficient measurement of expression of thousands genes simultaneously in a wide spectrum of experimental and clinical models. This genomic scale approach is being currently used to obtain global views of human cancer gene expression and to identify genetic markers that might be important for diagnosis, prognosis, and therapy. This review discusses some recent findings obtained by means of cDNA arrays investigating the human melanoma. (C) 2003 Wiley-Liss, Inc.

引用

页码：219 / 223

页数：5

共 63 条

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