Directed Blood Vessel Growth Using an Angiogenic Microfiber/Microparticle Composite Patch

被引：37

作者：

DeVolder, Rossi J. ^{[2
]}

Bae, Harim ^{[1
]}

Lee, Jonghwi ^{[1
]}

Kong, Hyunjoon ^{[2
]}

机构：

[1] Chung Ang Univ, Dept Chem Engn & Mat Sci, Seoul 156756, South Korea

[2] Univ Illinois, Inst Genom Biol, Dept Chem & Biomol Engn, Urbana, IL 61801 USA

来源：

ADVANCED MATERIALS | 2011年 / 23卷 / 28期

基金：

美国国家科学基金会;

关键词：

NANOFIBERS; MORPHOGENESIS; OPPORTUNITIES; MICROFIBERS; MEDICINE; MATRICES; CELLS; VEGF;

D O I：

10.1002/adma.201100823

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

An angiogenic microfiber patch that releases angiogenic growth factors along aligned fibers and subsequently directs the spacing and orientation of mature and functional blood vessel formation is presented. The fiber patches are prepared by electrostatically binding electrosprayed vascular endothelial growth factor (VEGF)-encapsulating poly(lactide-co-glycolide) (PLGA) microparticles with electrospun poly(lactide) (PLA) microfibers.

引用

页码：3139 / +

页数：6

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