Oxygen depletion-induced dormancy in Mycobacterium bovis BCG

被引：110

作者：

Lim, A ^{[1
]}

Eleuterio, M ^{[1
]}

Hutter, B ^{[1
]}

Murugasu-Oei, B ^{[1
]}

Dick, T ^{[1
]}

机构：

[1] Inst Mol & Cell Biol, Singapore 117609, Singapore

来源：

JOURNAL OF BACTERIOLOGY | 1999年 / 181卷 / 07期

关键词：

D O I：

10.1128/JB.181.7.2252-2256.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Gradual depletion of oxygen causes the shift-down of aerobic growing Mycobacterium bovis BCG to an anaerobic synchronized state of nonreplicating persistence. The persistent culture shows induction of glycine dehydrogenase and alpha-crystallin-like protein and is sensitive to metronidazole.

引用

页码：2252 / 2256

页数：5

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