Never synthesis of a water-soluble cyclodextrin-polymer having a chitosan skeleton

被引：42

作者：

Tanida, F

Tojima, T

Han, SM

Nishi, N

Tokura, S

Sakairi, N ^{[1
]}

Seino, H

Hamada, K

机构：

[1] Hokkaido Univ, Grad Sch Environm Earth Sci, Div Biosci, Sapporo, Hokkaido 060, Japan

[2] PIAS Corp, Nishi Ku, Kobe, Hyogo 65122, Japan

[3] ACSEINE Corp, Kita Ku, Osaka 531, Japan

来源：

POLYMER | 1998年 / 39卷 / 21期

关键词：

chitosan; cyclodextrin; inclusion ability;

D O I：

10.1016/S0032-3861(97)10206-3

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Formation of Schiff's base between 2-O-(formylmethyl)-beta-cyclodextrin and chitosan with an average molecular weight of 40 000 in acetate buffer at pH 4.4, followed by reduction with sodium cyanoborohydride produced a beta-cyclodextrin-linked chitosan in a one-pot reaction. The product, which had a degree of substitution of 37%, was soluble in water at neutral and alkaline conditions. UV-visible and circular dichroism spectroscopic examinations revealed that the product had the ability to form a host-guest complex with p-nitrophenolate. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5261 / 5263

页数：3