Achieving serum urate targets in gout: an audit in a gout-oriented rheumatology practice

被引：21

作者：

Corbett, Elizabeth J. M. ^{[1
]}

Pentony, Peta ^{[2
]}

McGill, Neil W. ^{[1
,3
]}

机构：

[1] Royal Prince Alfred Hosp, Sydney, NSW, Australia

[2] Royal Prince Alfred Hosp, Dept Rheumatol, Sydney, NSW, Australia

[3] Univ Sydney, Dept Rheumatol, Sydney, NSW, Australia

来源：

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES | 2017年 / 20卷 / 07期

关键词：

adherence; gout; urate; LOWERING THERAPY; MANAGEMENT;

D O I：

10.1111/1756-185X.13032

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

AimTo assess the proportion of patients with gout who achieve target serum urate levels, the drug regime required and the reasons for failing to do so. MethodsWe reviewed the files of all patients with gout who presented to a gout-oriented rheumatology practice between January 2010 and September 2014. ResultsTwo hundred and thirty patients agreed to commence urate lowering therapy (ULT); 73% achieved their urate target, including 74% with non-tophaceous gout (target 0.36mmol/L) and 71% with tophi (target 0.30mmol/L). Of the 62 who failed to reach target, in 61 it was due to non-adherence and in one due to inefficacy. ConclusionAdherence remains the major challenge to successful long-term gout management.

引用

页码：894 / 897

页数：4

共 8 条

[1]

Medication Adherence in Gout: A Systematic Review [J].

De Vera, Mary A. ;

Marcotte, Greg ;

Rai, Sharan ;

Galo, Jessica S. ;

Bhole, Vidula .

ARTHRITIS CARE & RESEARCH, 2014, 66 (10) :1551-1559

[2]

Gout: why is this curable disease so seldom cured? [J].

Doherty, Michael ;

Jansen, Tim L. ;

Nuki, George ;

Pascual, Eliseo ;

Perez-Ruiz, Fernando ;

Punzi, Leonardo ;

So, Alexander K. ;

Bardin, Thomas .

ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 (11) :1765-1770

[3]

Gout, Urate-Lowering Therapy, and Uric Acid Levels Among Adults in the United States [J].

Juraschek, Stephen P. ;

Kovell, Lara C. ;

Miller, Edgar R. ;

Gelber, Allan C. .

ARTHRITIS CARE & RESEARCH, 2015, 67 (04) :588-592

[4]

Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study [J].

Kuo, Chang-Fu ;

Grainge, Matthew J. ;

Mallen, Christian ;

Zhang, Weiya ;

Doherty, Michael .

ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 (04) :661-667

[5]

Allopurinol adherence among patients with gout: an Italian general practice database study [J].

Mantarro, S. ;

Capogrosso-Sansone, A. ;

Tuccori, M. ;

Blandizzi, C. ;

Montagnani, S. ;

Convertino, I. ;

Antonioli, L. ;

Fornai, M. ;

Cricelli, I. ;

Pecchioli, S. ;

Cricelli, C. ;

Lapi, F. .

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 2015, 69 (07) :757-765

[6]

Effect of urate-lowering therapy on the velocity of size reduction of tophi in chronic gout [J].

Perez-Ruiz, F ;

Calabozo, M ;

Pijoan, J ;

Herrero-Beites, AM ;

Ruibal, A .

ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2002, 47 (04) :356-360

[7]

Robinson PC, 2015, RHEUMATOLOGY, V42, P9

[8]

Multinational evidence-based recommendations for the diagnosis and management of gout: integrating systematic literature review and expert opinion of a broad panel of rheumatologists in the 3e initiative [J].

Sivera, Francisca ;

Andres, Mariano ;

Carmona, Loreto ;

Kydd, Alison S. R. ;

Moi, John ;

Seth, Rakhi ;

Sriranganathan, Melonie ;

van Durme, Caroline ;

van Echteld, Irene ;

Vinik, Ophir ;

Wechalekar, Mihir D. ;

Aletaha, Daniel ;

Bombardier, Claire ;

Buchbinder, Rachelle ;

Edwards, Christopher J. ;

Landewe, Robert B. ;

Bijlsma, Johannes W. ;

Branco, Jaime C. ;

Burgos-Vargas, Ruben ;

Catrina, Anca I. ;

Elewaut, Dirk ;

Ferrari, Antonio J. L. ;

Kiely, Patrick ;

Leeb, Burkhard F. ;

Montecucco, Carlomaurizio ;

Mueller-Ladner, Ulf ;

Ostergaard, Mikkel ;

Zochling, Jane ;

Falzon, Louise ;

van der Heijde, Desiree M. .

ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 (02) :328-335

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