Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobactetiaceae

被引：286

作者：

Anderson, K. F. ^{[1
]}

Lonsway, D. R. ^{[1
]}

Rasheed, J. K. ^{[1
]}

Biddle, J. ^{[1
]}

Jensen, B. ^{[1
]}

McDougal, L. K. ^{[1
]}

Carey, R. B. ^{[1
]}

Thompson, A. ^{[1
]}

Stocker, S. ^{[1
]}

Limbago, B. ^{[1
]}

Patel, J. B. ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30333 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2007年 / 45卷 / 08期

关键词：

D O I：

10.1128/JCM.00015-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The Klebsiella pneumoniae carbapenem (KPC) beta-lactamase occurs in Enterobacteriaceae and can confer resistance to all beta-lactam agents including carbapenems. The enzyme may confer low-level carbapenem resistance, and the failure of susceptibility methods to identify this resistance has been reported. Automated and nonautomated methods for carbapenem susceptibility were evaluated for identification of KPC-mediated resistance. Ertapenem was a more sensitive indicator of KPC resistance than meropenem and imipenem independently of the method used. Carbapenemase production could be confirmed with the modified Hodge test.

引用

页码：2723 / 2725

页数：3

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