Peroxisomes: minted by the ER

被引:47
作者
Tabak, Henk F. [1 ]
van der Zand, Adabella [1 ]
Braakman, Ineke [1 ]
机构
[1] Univ Utrecht, Bijvoet Ctr Biomol Res, NL-3584 CH Utrecht, Netherlands
关键词
D O I
10.1016/j.ceb.2008.05.008
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Peroxisomes are one of numerous organelles in a eukaryotic cell; they are small, sing le-membrane-bound vesicles involved in cellular metabolism, particularly fatty acid degradation. Transport of metabolites and co-factors in and across the membrane is taken care of by specific transporters. Peroxisome formation and maintenance has been debated for a long time: opinions swinging from autonomous to ER-derived organelles. Only recently it has been established firmly that the site of origin of peroxisomes is the ER. It implies that a new branch of the endomembrane system is open to further characterization.
引用
收藏
页码:393 / 400
页数:8
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