Cortical reorganization in patients with high frequency cochlear hearing loss

被引：112

作者：

Dietrich, V

Nieschalk, M

Stoll, W

Rajan, R

Pantev, C

机构：

[1] Univ Munster, Dept Otorhinolaryngol, D-48129 Munster, Germany

[2] Univ Munster, Inst Expt Audiol, Ctr Biomagnetism, D-48129 Munster, Germany

[3] Monash Univ, Dept Psychol, Clayton, Vic 3168, Australia

[4] Univ Toronto, Rotman Res Inst Neurosci, Toronto, ON M6A 2E1, Canada

来源：

HEARING RESEARCH | 2001年 / 158卷 / 1-2期

关键词：

cortical plasticity; magnetoencephalography; auditory cortex; auditory evoked field;

D O I：

10.1016/S0378-5955(01)00282-9

中图分类号：

R36 [病理学]; R76 [耳鼻咽喉科学];

学科分类号：

100104 ; 100213 ;

摘要：

Animal research has shown that tonotopic representation in the auditory cortex is not statically fixed in the adult organism but can be altered after deafferentation. The present study examines the plasticity of the human auditory cortex in patients with high frequency cochlear hearing loss by means of magnetoencephalographic measurements. The data show that the cortical map can reorganize such that cortical neurons deprived of their usual most sensitive afferent input now respond to tone frequencies adjacent to the frequency range of the partial hearing loss. The results suggest that deafferentation due to cochlear damage in adults may lead to functional reorganization of auditory cortical structures. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：95 / 101

页数：7

共 27 条

[21] PROCESSING OF COMPLEX SOUNDS IN THE MACAQUE NONPRIMARY AUDITORY-CORTEX [J].