Regulatory T cells control the development of allergic disease and asthma

被引：178

作者：

Umetsu, DT ^{[1
]}

Akbari, O ^{[1
]}

DeKruyff, RH ^{[1
]}

机构：

[1] Stanford Univ, Dept Pediat, Div Immunol & Allergy, Stanford, CA 94305 USA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2003年 / 112卷 / 03期

关键词：

T regulatory cells; T(H)2; asthma; allergy;

D O I：

10.1067/mai.2003.1717

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The role of T(H)2 cells in the pathogenesis of allergy and asthma has been well described. However, the immunologic mechanisms that downmodulate and protect against the development of these disorders are poorly characterized. A spectrum of CD4(+) T cells, including T(H)1 cells, T(H)3 cells, regulatory T cells, CD25(+) T cells, and natural killer T cells might play a critical role in regulating these diseases and are discussed in this review.

引用

页码：480 / 487

页数：8

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