Novel intramolecular rearrangement of 3-bromo-3,3-difluoroalanine Schiff bases via radical ipso-substitution at the aromatic ring

被引：37

作者：

Amii, H ^{[1
]}

Kondo, S ^{[1
]}

Uneyama, K ^{[1
]}

机构：

[1] Okayama Univ, Fac Engn, Dept Appl Chem, Okayama 7000082, Japan

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 17期

关键词：

D O I：

10.1039/a803944e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3-Bromo-3,3-difluoroalanine Schiff bases are synthesized by bromodifluoromethylation of the corresponding glycine Schiff bases with CF2Br2; their intramolecular rearrangement involving radical ipso-substitution at the aromatic ring of the imine moiety provides 3,3-difluoro-3-arylpropanoates in good yields.

引用

页码：1845 / 1846

页数：2

共 12 条

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