Outcomes of early language delay: II. Etiology of transient and persistent language difficulties

被引:75
作者
Bishop, DVM
Price, TS
Dale, PS
Plomin, R
机构
[1] Univ Missouri, Columbia, MO 65211 USA
[2] Univ Oxford, Oxford, England
[3] Inst Psychiat, London, England
来源
JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH | 2003年 / 46卷 / 03期
关键词
language delay; preschoolers; genetic influence; longitudinal outcome;
D O I
10.1044/1092-4388(2003/045)
中图分类号
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号
100104 ; 100213 ;
摘要
Genes are known to play an important role in causing specific language impairment, but it is unclear how far a similar etiology is implicated in transient, language delay in early childhood. Two-year-old children with vocabulary scores below the 10th centile were selected from a cohort of over 2,800 same-sex twin pairs whose language was assessed by parental report at 2, 3, and A years of age. These children with early language delay (ELD) were divided into cases of transient and persistent language difficulties on the basis of outcome at 3 and A years. A DeFries-Fulker analysis (J. C. DeFries & D. W. Fulker, 1985) was used to compute group heritability (h(g)(2)) of 2-year vocabulary delay separately for those with transient and persistent difficulties. When 3-year and 4-year language attainments were used to categorize outcomes, h(g)(2) was similar and modest (.25 or less) for both transient and persistent difficulties'. However, when persistent difficulties were defined according to whether parents expressed concern about language at 3 years or according to whether a professional had been consulted about language difficulties at A years, heritability was significantly higher. For 289 children with no professional involvement at A years, heritability of 2-year vocabulary delay was close to zero, whereas for 134 children with professional involvement, a significant h(g)(2) of .41 (SE =.127) was found. Early language delay appears largely environmental in origin for 2-year-olds whose parents do not go. on to seek professional help.
引用
收藏
页码:561 / 575
页数:15
相关论文
共 36 条
[1]  
[Anonymous], 2000, Speech and Language Impairments in Children: Causes, Characteristics, Intervention and Outcome
[3]  
BISHOP DVM, 1995, DEV MED CHILD NEUROL, V37, P56
[4]   Varieties of developmental reading disorder: Genetic and environmental influences [J].
Castles, A ;
Datta, H ;
Gayan, J ;
Olson, RK .
JOURNAL OF EXPERIMENTAL CHILD PSYCHOLOGY, 1999, 72 (02) :73-94
[5]  
Dale P. S., 1991, LANG SPEECH HEAR SER, V22, P80, DOI DOI 10.1044/0161-1461.2202.80
[6]   Genetic influence on language delay in two-year-old children [J].
Dale, PS ;
Simonoff, E ;
Bishop, DVM ;
Eley, TC ;
Oliver, B ;
Price, TS ;
Purcell, S ;
Stevenson, J ;
Plomin, R .
NATURE NEUROSCIENCE, 1998, 1 (04) :324-328
[7]   Outcomes of early language delay: I. Predicting persistent and transient language difficulties at 3 and 4 years [J].
Dale, PS ;
Price, TS ;
Bishop, DVM ;
Plomin, R .
JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH, 2003, 46 (03) :544-560
[8]   MULTIPLE-REGRESSION ANALYSIS OF TWIN DATA [J].
DEFRIES, JC ;
FULKER, DW .
BEHAVIOR GENETICS, 1985, 15 (05) :467-473
[9]   Genetic evidence for bidirectional effects of early lexical and grammatical development [J].
Dionne, G ;
Dale, PS ;
Boivin, M ;
Plomin, R .
CHILD DEVELOPMENT, 2003, 74 (02) :394-412
[10]  
eonard L., 1987, ADV APPL PSYCHOLINGU, V1, P1