Influence of nonexcitable cells on spiral breakup in two-dimensional and three-dimensional excitable media

被引：64

作者：

ten Tusscher, KHWJ

Panfilov, AV

机构：

[1] Univ Utrecht, Dept Theoret Biol, NL-3584 CH Utrecht, Netherlands

[2] Univ Dundee, Div Math, Dundee DD1 4HN, Scotland

来源：

PHYSICAL REVIEW E | 2003年 / 68卷 / 06期

关键词：

D O I：

10.1103/PhysRevE.68.062902

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

We study spiral wave dynamics in the presence of nonexcitable cells in two-dimensional (2D) and three-dimensional (3D) excitable media, described by the Aliev-Panfilov model. We find that increasing the percentage of randomly distributed nonexcitable cells can prevent the breaking up of a spiral wave into a complex spatiotemporal pattern. We show that this effect is more pronounced in 2D than 3D excitable media. We explain the observed 2D vs 3D differences by a different dependence of the period and diastolic interval of the spiral wave on the percentage of nonexcitable cells in 2D and 3D excitable media.

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页数：4

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