Acute renal failure on immune reconstitution in an HIV-positive patient with miliary tuberculosis

被引:34
作者
Jehle, AW
Khanna, N
Sigle, JP
Glatz-Krieger, K
Battegay, M
Steiger, J
Dickenmann, M
Hirsch, HH
机构
[1] Univ Basel Hosp, Div Infect Dis, CH-4031 Basel, Switzerland
[2] Univ Basel Hosp, Div Transplantat Immunol & Nephrol, CH-4031 Basel, Switzerland
[3] Univ Basel Hosp, Inst Pathol, CH-4031 Basel, Switzerland
[4] Univ Basel Hosp, Dept Med Microbiol, CH-4031 Basel, Switzerland
关键词
D O I
10.1086/381441
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Immune reconstitution syndrome following HAART in human immunodeficiency virus (HIV)-infected patients is characterized by inflammatory worsening of organ functions despite improvement in HIV surrogate markers of HIV infection. We describe a patient with miliary tuberculosis and urinary shedding of acid fast bacilli who developed acute renal failure 8 weeks after initiation of antituberculosis therapy and 6 weeks after initiation of HAART. The diagnostic workup and further course of disease implicated immune reconstitution syndrome as the cause of acute renal failure.
引用
收藏
页码:E32 / E35
页数:4
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