A hybrid plasmonic-photonic nanodevice for label-free detection of a few molecules

被引:191
作者
De Angelis, Francesco [1 ,2 ]
Patrini, Maddalena [3 ,4 ]
Das, Gobind [1 ,2 ]
Maksymov, Ivan [3 ,4 ]
Galli, Matteo [3 ,4 ]
Businaro, Luca [5 ]
Andreani, Lucio Claudio [3 ,4 ]
Di Fabrizio, Enzo [1 ,2 ,5 ]
机构
[1] Magna Graecia Univ Catanzaro, BIONEM Lab, I-88100 Catanzaro, Italy
[2] CalMED Srl, I-88100 Catanzaro, Italy
[3] Univ Pavia, CNISM, I-27100 Pavia, Italy
[4] Univ Pavia, Dept Phys A Volta, I-27100 Pavia, Italy
[5] CNR INFM, TASC Natl Lab, I-34012 Trieste, Italy
关键词
D O I
10.1021/nl801112e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Noble metal nanowaveguides supporting plasmon polariton modes are able to localize the optical fields at nanometer level for high sensitivity biochemical sensing devices. Here we report on the design and fabrication of a novel photonic-plasmonic device which demonstrates label-free detection capabilities on single inorganic nanoparticles and on monolayers of organic compounds. In any case, we determine the Raman scattering signal enhancement and the device detection limits that reach a number of molecules between 10 and 250. The device can be straightforwardly integrated in a scanning probe apparatus with the possibility to match topographic and label-free spectroscopic information in a wide range of geometries.
引用
收藏
页码:2321 / 2327
页数:7
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