Biomolecules-carbon nanotubes doped conducting polymer nanocomposites and their sensor application

被引：51

作者：

Kum, Maxwell C.

Joshi, Kanchan A.

Chen, Wilfred

Myung, Nosang V.

Mulchandani, Ashok ^{[1
]}

机构：

[1] Univ Calif Riverside, Dept Chem & Environm Engn, Riverside, CA 92521 USA

来源：

TALANTA | 2007年 / 74卷 / 03期

基金：

美国国家科学基金会;

关键词：

carbon nanotubes; biomolecule; conducting polymer; polypyrrole; nanocomposite; biosensor;

D O I：

10.1016/j.talanta.2007.08.047

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A simple method for preparing bio-functionalized soluble single-walled carbon nanotubes (SWNTs) is described. Different proteins such as bovine serum albumin (BSA), cytochrome c and horseradish peroxidase (HRP) were used to solubilize low functionality SWNTs in water aided by sonication. The unbound proteins were removed by column chromatography and the SWNT-protein conjugate was used as the sole anionic dopant in electropolymerization of polypyrrole from polymerization solution at pH above the isoelectric point of the protein to provide a negative charge. The morphology of the polypyrrole with SWNT-protein dopant was found to be three-dimensional and fibrous with wide open interlocking pores in contrast to smooth and cauliflower-like for chloride doped polypyrrole. Enhanced sensor performance was demonstrated for hydrogen peroxide detection on polypyrrole/SWCNT-HRP nanocomposites modified electrode. Such nanocomposites can be potentially applied for other biosensor and bio-fuel cell applications. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：370 / 375

页数：6

共 43 条

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