TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases

被引：481

作者：

Feldmann, M ^{[1
]}

Maini, RN ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Fac Med, Kennedy Inst, Div Rheumatol, London W6 8LH, England

来源：

NATURE MEDICINE | 2003年 / 9卷 / 10期

关键词：

D O I：

10.1038/nm939

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1245 / 1250

页数：6

共 35 条

[11] REPEATED THERAPY WITH MONOCLONAL-ANTIBODY TO TUMOR-NECROSIS-FACTOR-ALPHA (CA2) IN PATIENTS WITH RHEUMATOID-ARTHRITIS [J].

ELLIOTT, MJ ;

MAINI, RN ;

FELDMANN, M ;

LONGFOX, A ;

CHARLES, P ;

BIJL, H ;

WOODY, JN .

LANCET, 1994, 344 (8930) :1125-1127

[12] Anti-TNFα therapy of rheumatoid arthritis:: what have we learned? [J].

Feldmann, M ;

Maini, RN .

ANNUAL REVIEW OF IMMUNOLOGY, 2001, 19 :163-196

[13] Role of cytokines in rheumatoid arthritis [J].

Feldmann, M ;

Brennan, FM ;

Maini, RN .

ANNUAL REVIEW OF IMMUNOLOGY, 1996, 14 :397-440

[14] ANTIBODIES TO CACHECTIN TUMOR NECROSIS FACTOR REDUCE INTERLEUKIN-1-BETA AND INTERLEUKIN-6 APPEARANCE DURING LETHAL BACTEREMIA [J].

FONG, YM ;

TRACEY, KJ ;

MOLDAWER, LL ;

HESSE, DG ;

MANOGUE, KB ;

KENNEY, JS ;

LEE, AT ;

KUO, GC ;

ALLISON, AC ;

LOWRY, SF ;

CERAMI, A .

JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 170 (05) :1627-1633

[15] EXPRESSION OF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR IN RHEUMATOID-ARTHRITIS - REGULATION BY TUMOR-NECROSIS-FACTOR-ALPHA [J].

HAWORTH, C ;

BRENNAN, FM ;

CHANTRY, D ;

TURNER, M ;

MAINI, RN ;

FELDMANN, M .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1991, 21 (10) :2575-2579

[16]

JANOSSY G, 1981, LANCET, V2, P839

[17] TRANSGENIC MICE EXPRESSING HUMAN TUMOR-NECROSIS-FACTOR - A PREDICTIVE GENETIC MODEL OF ARTHRITIS [J].

KEFFER, J ;

PROBERT, L ;

CAZLARIS, H ;

GEORGOPOULOS, S ;

KASLARIS, E ;

KIOUSSIS, D ;

KOLLIAS, G .

EMBO JOURNAL, 1991, 10 (13) :4025-4031

[18] EVIDENCE IN SUPPORT OF A SELF-PERPETUATING HLA-DR-DEPENDENT DELAYED-TYPE CELL REACTION IN RHEUMATOID-ARTHRITIS [J].

KLARESKOG, L ;

FORSUM, U ;

SCHEYNIUS, A ;

KABELITZ, D ;

WIGZELL, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (11) :3632-3636

[19] Infliximab and methotrexate in the treatment of rheumatoid arthritis [J].

Lipsky, PE ;

van der Heijde, DMFM ;

St Clair, EW ;

Furst, DE ;

Breedveld, FC ;

Kalden, JR ;

Smolen, JS ;

Weisman, M ;

Emery, P ;

Feldmann, M ;

Harriman, GR ;

Maini, RN .

NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (22) :1594-1602

[20]

Maini RN, 1998, ARTHRITIS RHEUM, V41, P1552, DOI 10.1002/1529-0131(199809)41:9<1552::AID-ART5>3.0.CO

← 1 2 3 4 →