Antigenic variation in babesiosis: is there more than one 'why'?

被引：17

作者：

Allred, DR ^{[1
]}

机构：

[1] Univ Florida, Dept Pathobiol, Gainesville, FL 32611 USA

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 06期

关键词：

antigenic variation; Babesia bovis; babesiosis; gene conversion;

D O I：

10.1016/S1286-4579(01)01404-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Many intraerythrocytic hemoparasites survive the host immune system through rapid antigenic variation. Among babesial parasites antigenic variation has been demonstrated convincingly only for Babesia bovis and Babesia rodhaini. The molecular basis for antigenic variation in babesial parasites and its possible connection with cytoadherence and sequestration are discussed. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

页码：481 / 491

页数：11

共 56 条

[1] IMMUNE EVASION BY BABESIA-BOVIS AND PLASMODIUM-FALCIPARUM - CLIFF-DWELLERS OF THE PARASITE WORLD [J].

ALLRED, DR .

PARASITOLOGY TODAY, 1995, 11 (03) :100-105

[2] ISOLATE-SPECIFIC PARASITE ANTIGENS OF THE BABESIA-BOVIS-INFECTED ERYTHROCYTE SURFACE [J].

ALLRED, DR ;

HINES, SA ;

AHRENS, KP .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1993, 60 (01) :121-132

[3] The ves multigene family of B-bovis encodes components of rapid antigenic variation at the infected erythrocyte surface [J].

Allred, DR ;

Carlton, JMR ;

Satcher, RL ;

Long, JA ;

Brown, WC ;

Patterson, PE ;

O'Connor, RM ;

Stroup, SE .

MOLECULAR CELL, 2000, 5 (01) :153-162

[4] ANTIGENIC VARIATION OF PARASITE-DERIVED ANTIGENS ON THE SURFACE OF BABESIA BOVIS-INFECTED ERYTHROCYTES [J].

ALLRED, DR ;

CINQUE, RM ;

LANE, TJ ;

AHRENS, KP .

INFECTION AND IMMUNITY, 1994, 62 (01) :91-98

[5] Identification of a region of PfEMP1 that mediates adherence of Plasmodium falciparum infected erythrocytes to CD36: Conserved function with variant sequence [J].

Baruch, DI ;

Ma, XC ;

Singh, HB ;

Bi, XH ;

Pasloske, BL ;

Howard, RJ .

BLOOD, 1997, 90 (09) :3766-3775

[6] ANTIGENIC VARIATION IN PLASMODIUM-FALCIPARUM [J].

BIGGS, BA ;

GOOZE, L ;

WYCHERLEY, K ;

WOLLISH, W ;

SOUTHWELL, B ;

LEECH, JH ;

BROWN, GV .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (20) :9171-9174

[7] IMMUNITY TO MALARIA - ANTIGENIC VARIATION IN CHRONIC INFECTIONS OF PLASMODIUM KNOWLESI [J].

BROWN, KN ;

BROWN, IN .

NATURE, 1965, 208 (5017) :1286-&

[8] Designing blood-stage vaccines against Babesia bovis and B-bigemina [J].

Brown, WC ;

Palmer, GH .

PARASITOLOGY TODAY, 1999, 15 (07) :275-281

[9] Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria [J].

Bull, PC ;

Lowe, BS ;

Kortok, M ;

Molyneux, CS ;

Newbold, CI ;

Marsh, K .

NATURE MEDICINE, 1998, 4 (03) :358-360

[10] Monitoring Babesia bovis infections in cattle by using PCR-based tests [J].

Calder, JAM ;

Reddy, GR ;

Chieves, L ;

Courtney, CH ;

Littell, R ;

Livengood, JR ;

Norval, RAI ;

Smith, C ;

Dame, JB .

JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (11) :2748-2755

← 1 2 3 4 5 6 →