Electrochemical Detection of Uric Acid in Mixed and Clinical Samples: A Review

被引:211
作者
Lakshmi, Dhana [1 ]
Whitcombe, Michael J. [1 ]
Davis, Frank [1 ]
Sharma, Piyush Sindhu [3 ]
Prasad, Bhim Bali [2 ]
机构
[1] Cranfield Univ, Cranfield MK43 0AL, Beds, England
[2] Banaras Hindu Univ, Analyt Div, Dept Chem, Varanasi 221005, Uttar Pradesh, India
[3] Univ Verona, Dept Biotechnol, I-37100 Verona, Italy
关键词
Uric acid; Polymer modified electrode; Sensors; Electrochemistry; GLASSY-CARBON ELECTRODE; SELECTIVE VOLTAMMETRIC METHOD; OVEROXIDIZED POLYPYRROLE FILMS; CHEMICALLY-MODIFIED ELECTRODES; ASCORBIC-ACID; AMPEROMETRIC BIOSENSOR; COMPOSITE ELECTRODES; GOLD NANOPARTICLES; PASTE ELECTRODE; CATALYTIC-OXIDATION;
D O I
10.1002/elan.201000525
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The present review has sought to explore the technological advances that have been made in recent years towards the selective analysis of uric acid and critically evaluate how they could, in fact, be exploited as a basis for a multi analyte sensor incorporating uric acid detection. Numerous strategies have evolved in recent years but these have invariably focused on the manufacture and response characterization of discrete sensors. Various methods of obtaining selective detection such as use of uricase enzymes, nanoparticles, carbon nanotubes, polymers, conducting polymers and MIPs are also discussed along with the clinical relevance of UA determination.
引用
收藏
页码:305 / 320
页数:16
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