A stereospecific synthesis of tetra-substituted chiral piperazines

被引：14

作者：

Abdel-Jalil, RJ ^{[1
]}

Al-Qawasmeh, RA ^{[1
]}

Al-Abed, Y ^{[1
]}

Voelter, W ^{[1
]}

机构：

[1] Univ Tubingen, Inst Physiol Chem, Phys Biochem Abt, D-72076 Tubingen, Germany

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 42期

关键词：

anhydro sugars; piperazine derivatives; chiral piperazines;

D O I：

10.1016/S0040-4039(98)01677-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one pot reaction of the epoxy triflates 1 or 2 with a variety of N,N'-disubstituted ethylenediamines yields the corresponding chiral piperazine derivatives 3a-e and 4a-e of potential pharmacological interest in high yields, (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：7703 / 7704

页数：2

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