Structures of merrilactones B and C, novel anislactone-type sesquiterpenes from Illicium merrillianum, and chemical conversion of anislactone B to merrilactone A

被引：70

作者：

Huang, JM

Yang, CS

Tanaka, M

Fukuyama, Y ^{[1
]}

机构：

[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Inst Pharmacognosy, Tokushima 7708514, Japan

[2] Beijing Univ Chinese Med, Fac Chinese Pharmaceut Sci, Beijing 100029, Peoples R China

来源：

TETRAHEDRON | 2001年 / 57卷 / 22期

关键词：

Illicium; sesquiterpene; structure; synthesis; anislactone; merrilactone;

D O I：

10.1016/S0040-4020(01)00418-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new anislactone-type sesquiterpenes, merrilactones B (1) and C (2) were isolated from the pericarps of Illicium merrillianum along with anislactones A (4) and B (5). Their structures were elucidated by spectroscopic methods and chemical transformation and the structure of merrilactone C was established by X-ray crystallographic analysis of its methyl derivative. Merrilactone A (3), a unique anislactone-type sesquiterpene showing neurite outgrowth promoting activity, was effectively synthesized from anislactone B. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：4691 / 4698

页数：8

共 19 条

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