Supported gold(III) catalysts for highly efficient three-component coupling reactions

被引:249
作者
Zhang, Xin [1 ]
Corma, Avelino [1 ]
机构
[1] Univ Politecn Valencia, Inst Tecnol Quim, CSIC, Valencia 46022, Spain
关键词
alkynes; gold; homogeneous catalysis; multicomponent reactions; supported catalysts;
D O I
10.1002/anie.200800098
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Chemical Equation Presented) Charged gold species stabilized on nanocrystalline CeO2 or ZrO2 are highly active catalysts for the one-pot, three-component coupling of aldehydes, amines, and alkynes/N-protected ethynylaniline, which yields multifunctionalized propargylamines and indoles in good to excellent yields (see picture; Ts=toluene-4-sulfonyl). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:4358 / 4361
页数:4
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