Cytotoxicity of ferrite particles by MTT and agar diffusion methods for hyperthermic application

被引：78

作者：

Kim, DH

Lee, SH

Kim, KN

Kim, KM

Shim, IB

Lee, YK ^{[1
]}

机构：

[1] Yonsei Univ, Coll Dent, Brain Korea Project Med Sci 21, Seoul 120752, South Korea

[2] Yonsei Univ, Coll Dent, Dept Dent Biomat & Bioengn, Seoul 120752, South Korea

[3] Yonsei Univ, Coll Dent, Res Inst Dent Biomat & Bioengn, Seoul 120752, South Korea

[4] Kookmin Univ, Dept Phys Elect, Seoul 136702, South Korea

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2005年 / 293卷 / 01期

关键词：

ferrite; hyperthermia; MTT assay; agar overlay assay; cytotoxicity; toxicity; SrFe12O19; magnetite; biocompatibility; cobalt ferrite; Co/Ni ferrite;

D O I：

10.1016/j.jmmm.2005.02.078

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

We investigated the cytotoxicity of the prepared various ferrites (Fe-, Li-, Ni/Zn/Cu-, Ba-, Sr-, Co-, Co/Ni-ferrites) using MTT assay as well as agar diffusion method. Their cytotoxicity was compared with that of alginate-encapsulated ferrites. In the MTT assay, Fe3O4 and SrFe12O19 ferrite showed the highest cell viability of 90%. Alginate-encapsulated Ba-ferrite was ranked mildly cytotoxic, whereas their ferrite particles were ranked cytotoxic. (c) 2005 Published by Elsevier B.V.

引用

页码：287 / 292

页数：6

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