The prospects for developing a vaccine against Staphylococcus aureus

被引：47

作者：

Lee, JC ^{[1
]}

机构：

[1] HARVARD UNIV,BRIGHAM & WOMENS HOSP,SCH MED,CHANNING LAB,BOSTON,MA 02115

来源：

TRENDS IN MICROBIOLOGY | 1996年 / 4卷 / 04期

关键词：

D O I：

10.1016/0966-842X(96)10021-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Staphylococcus aureus is an important bacterial pathogen with multiple virulence factors. The prevalence of antibiotic resistance among clinical isolates means that new vaccine strategies to prevent staphylococcal infections are needed. An ideal vaccine would induce antibodies to prevent bacterial adherence, promote opsonophagocytic killing by leukocytes and neutralize toxic secreted proteins.

引用

页码：162 / 166

页数：5

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