Effect of temperature on the optical properties of ex vivo human dermis and subdermis

被引:101
作者
Laufer, J [1 ]
Simpson, R
Kohl, M
Essenpreis, M
Cope, M
机构
[1] UCL, Dept Med Phys & Bioengn, London WC1E 6JA, England
[2] Boehringer Mannheim GmbH, D-63305 Mannheim, Germany
关键词
D O I
10.1088/0031-9155/43/9/004
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The effect of temperature on the optical properties of human dermis and subdermis as a function of near-infrared wavelength has been studied between 25 degrees C and 40 degrees C. Measurements were performed ex vivo on a total of nine skin samples taken from the abdomen of three individuals. The results show a reproducible effect of temperature on the transport scattering coefficient of dermis and subdermis. The relative change of the transport scattering coefficient showed an increase for dermis ((4.7 +/- 0.5) x 10(-3)degrees C(-1)) and a decrease for subdermis ((-1.4 +/- 0.28) x 10(-3)degrees C(-1)). Note that the magnitude of the temperature coefficient of scattering was greater for dermis than subdermis. A reproducible effect of temperature on the absorption coefficient could not be found within experimental errors. System reproducibility in transport scattering coefficient with repeated removal and repositioning of the same tissue sample at the same temperature was excellent at +/-0.35% for all measurements. This reproducibility enabled such small changes in scattering coefficient to be detected.
引用
收藏
页码:2479 / 2489
页数:11
相关论文
共 13 条
[1]   Correlation between blood glucose concentration in diabetics and noninvasively measured tissue optical scattering coefficient [J].
Bruulsema, JT ;
Hayward, JE ;
Farrell, TJ ;
Patterson, MS ;
Heinemann, L ;
Berger, M ;
Koschinsky, T ;
SandahlChristiansen, J ;
Orskov, H .
OPTICS LETTERS, 1997, 22 (03) :190-192
[2]   OPTICAL-ABSORPTION SPECTRA OF DEOXYHEMOGLOBIN AND OXYHEMOGLOBIN IN THE TEMPERATURE-RANGE 300-20-K - RELATION WITH PROTEIN DYNAMICS [J].
CORDONE, L ;
CUPANE, A ;
LEONE, M ;
VITRANO, E .
BIOPHYSICAL CHEMISTRY, 1986, 24 (03) :259-275
[3]  
Jacques S. L., 1996, OSA TOPS ADV OPTICAL, V2, P364
[4]   THEORY OF THE INTEGRATING SPHERE [J].
JACQUEZ, JA ;
KUPPENHEIM, HF .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA, 1955, 45 (06) :460-470
[5]  
JAYWANT S, 1993, P SOC PHOTO-OPT INS, V1882, P218, DOI 10.1117/12.148080
[6]   THE INFLUENCE OF GLUCOSE-CONCENTRATION UPON THE TRANSPORT OF LIGHT IN TISSUE-SIMULATING PHANTOMS [J].
KOHL, M ;
ESSENPREIS, M ;
COPE, M .
PHYSICS IN MEDICINE AND BIOLOGY, 1995, 40 (07) :1267-1287
[7]   PHYSICAL-PROPERTIES OF GLYCOSYLDIACYLGLYCEROLS - AN INFRARED SPECTROSCOPIC STUDY OF THE GEL-PHASE POLYMORPHISM OF 1,2-DI-O-ACYL-3-O-(BETA-D-GLUCOPYRANOSYL)-SN-GLYCEROLS [J].
LEWIS, RNAH ;
MANNOCK, DA ;
MCELHANEY, RN ;
WONG, PTT ;
MANTSCH, HH .
BIOCHEMISTRY, 1990, 29 (38) :8933-8943
[8]   THERMOTROPIC PHASE-BEHAVIOR OF MODEL MEMBRANES COMPOSED OF PHOSPHATIDYLCHOLINES CONTAINING DL-METHYL ANTEISOBRANCHED FATTY-ACIDS .2. AN INFRARED-SPECTROSCOPY STUDY [J].
MANTSCH, HH ;
MADEC, C ;
LEWIS, RNAH ;
MCELHANEY, RN .
BIOCHEMISTRY, 1987, 26 (13) :4045-4049
[9]   MIE AND RAYLEIGH MODELING OF VISIBLE-LIGHT SCATTERING IN NEONATAL SKIN [J].
SAIDI, IS ;
JACQUES, SL ;
TITTEL, FK .
APPLIED OPTICS, 1995, 34 (31) :7410-7418
[10]   Near infrared absorption spectra of human deoxy- and oxyhaemoglobin in the temperature range 20-40 degrees C [J].
Sfareni, R ;
Boffi, A ;
Quaresima, V ;
Ferrari, M .
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, 1997, 1340 (02) :165-169