Polyamine uptake systems in Escherichia coli

被引：73

作者：

Igarashi, K

Ito, K

Kashiwagi, K

机构：

[1] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

[2] Nagasaki Univ, Sch Pharmaceut Sci, Nagasaki 8528131, Japan

来源：

RESEARCH IN MICROBIOLOGY | 2001年 / 152卷 / 3-4期

关键词：

polyamines; putrescine; spermidine; uptake; excretion;

D O I：

10.1016/S0923-2508(01)01198-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The polyamine content of cells is regulated by biosynthesis, degradation, and transport. In Escherichia coli, the genes for three different polyamine transport systems have been cloned and characterized. Two uptake systems (putrescine-specific and spermidine-preferential) are ABC transporters, each consisting of a periplasmic substrate binding protein, two transmembrane proteins, and a membrane associated ATPase. The third transport system, catalyzed by PotE, mediates both uptake and excretion of putrescine. In this article, the properties of the first two polyamine uptake systems are reviewed in detail. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

收藏

页码：271 / 278

页数：8

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