Mild and efficient CS2CO3-promoted synthesis of phosphonates

被引：64

作者：

Cohen, RJ ^{[1
]}

Fox, DL ^{[1
]}

Eubank, JF ^{[1
]}

Salvatore, RN ^{[1
]}

机构：

[1] Western Kentucky Univ, Dept Chem, Bowling Green, KY 42101 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 47期

关键词：

phosphonate; dialkyl phosphite; cesium carbonate; tetrabutylammonium iodide;

D O I：

10.1016/j.tetlet.2003.09.045

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

mild and convenient synthesis for phosphonates using cesium carbonate (Cs2CO3), tetrabutylammonium iodide (TBAI) and DMF was developed at room temperature. Numerous dialkyl phosphites were screened using a diverse array of alkyl halides and these reaction conditions were found to be highly efficient producing various phosphonates exclusively in moderate to high yields. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：8617 / 8621

页数：5

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