The Botany Array Resource: e-Northerns, Expression Angling, and Promoter analyses

被引:570
作者
Toufighi, K
Brady, SM
Austin, R
Ly, E
Provart, NJ
机构
[1] Univ Toronto, Dept Bot, Toronto, ON M5S 3B2, Canada
[2] Inst Genom Res, Rockville, MD 20850 USA
关键词
microarray experiment; expression profile; promoter analysis; electronic Northern; data mining; Arabidopsis thaliana;
D O I
10.1111/j.1365-313X.2005.02437.x
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The Botany Array Resource provides the means for obtaining and archiving microarray data for Arabidopsis thaliana as well as biologist-friendly tools for viewing and mining both our own and other's data, for example, from the AtGenExpress Consortium. All the data produced are publicly available through the web interface of the database at http://bbc.botany.utoronto.ca. The database has been designed in accordance with the Minimum Information About a Microarray Experiment [Brazma, A., Hingamp, P., Quackenbush, J. et al. (2001) Minimum information about a microarray experiment (MIAME) - toward standards for microarray data. Nat. Genet.29, 365] convention - all expression data are associated with the corresponding experimental details. The database is searchable and it also provides a set of useful and easy-to-use web-based data-mining tools for researchers with sophisticated yet understandable output graphics. These include Expression Browser for performing 'electronic Northerns', Expression Angler for identifying genes that are co-regulated with a gene of interest, and Promomer for identifying potential cis-elements in the promoters of individual or co-regulated genes.
引用
收藏
页码:153 / 163
页数:11
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