Electroporation stimulates interleukin 10 production in human monocytic cell lines THP-1 and U937

被引：6

作者：

Lehmann, MH ^{[1
]}

Hoffken, K ^{[1
]}

Berg, H ^{[1
]}

机构：

[1] INST MOL BIOTECHNOL,LAB BIOELECTROCHEM,JENA,GERMANY

来源：

BIOELECTROCHEMISTRY AND BIOENERGETICS | 1996年 / 41卷 / 02期

关键词：

electroporative stimulation; interleukin; 10; monocytic cell; amplitude factor; time dependence; positive window;

D O I：

10.1016/S0302-4598(96)05127-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Interleukin-10 inhibit cytokine release by murine type 1 helper T-cells. It also increases the expression of the MHC II complex on the surface of B-cells and prolongs their vitality. Unexpected electrostimulation of IL-10 in the human monocytic cell lines THP-1 and U937 by strong single exponential pulses is reported. The stimulation depends on the amplitude, pulse duration and the time after pulse treatment.

引用

页码：227 / 229

页数：3