Advances in proteome analysis by mass spectrometry

被引：65

作者：

Griffin, TJ ^{[1
]}

Goodlett, DR ^{[1
]}

Aebersold, R ^{[1
]}

机构：

[1] Inst Syst Biol, Seattle, WA 98105 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2001年 / 12卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0958-1669(01)00268-3

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Proteome characterization using mass spectrometry is essential for the systematic investigation of biological systems and for the study of gene function. Recent advances in this multifaceted field have occurred in four general areas: protein and peptide separation methodologies; selective labeling chemistries for quantitative measurement of peptide and protein abundances; characterization of post-translational protein modifications; and instrumentation.

引用

页码：607 / 612

页数：6

共 57 条

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[7] 2-B
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