1-[2-(2-hydroxyalkyl)phenyl]ethanone: A new photoremovable protecting group for carboxylic acids

被引：17

作者：

Atemnkeng, WN ^{[1
]}

Louisiana, LD ^{[1
]}

Yong, PK ^{[1
]}

Vottero, B ^{[1
]}

Banerjee, A ^{[1
]}

机构：

[1] Univ N Dakota, Dept Chem, Grand Forks, ND 58202 USA

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 23期

关键词：

D O I：

10.1021/ol035782q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new photoremovable protecting group for carboxylic acids is introduced. The protecting group 1-[2-(2-hydroxyalkyl)phenyl]ethanone, HAPE, is used to protect various carboxylic acids. When photolyzed, the protected compound releases the acid in 70-85% isolated yields. The synthesis and the results of photorelease of the protected acids are presented here.

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页码：4469 / 4471

页数：3

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