Iron is hot: An update on the pathophysiology of hemochromatosis

被引:78
作者
Andrews, NC
Levy, JE
机构
[1] Childrens Hosp, Howard Hughes Med Inst, Boston, MA 02115 USA
[2] Childrens Hosp, Div Hematol Oncol, Boston, MA 02115 USA
[3] Harvard Univ, Sch Med, Dept Pediat, Boston, MA 02115 USA
[4] Brigham & Womens Hosp, Div Hematol Oncol, Boston, MA 02115 USA
关键词
D O I
10.1182/blood.V92.6.1845.418k35_1845_1851
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1845 / 1851
页数:7
相关论文
共 74 条
  • [21] UPTAKE OF TRANSFERRIN-BOUND AND NONTRANSFERRIN-BOUND IRON BY RETICULOCYTES FROM THE BELGRADE LABORATORY RAT - COMPARISON WITH WISTAR RAT TRANSFERRIN AND RETICULOCYTES
    FARCICH, EA
    MORGAN, EH
    [J]. AMERICAN JOURNAL OF HEMATOLOGY, 1992, 39 (01) : 9 - 14
  • [22] The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding
    Feder, JN
    Penny, DM
    Irrinki, A
    Lee, VK
    Lebrón, JA
    Watson, N
    Tsuchihashi, Z
    Sigal, E
    Bjorkman, PJ
    Schatzman, RC
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (04) : 1472 - 1477
  • [23] A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
    Feder, JN
    Gnirke, A
    Thomas, W
    Tsuchihashi, Z
    Ruddy, DA
    Basava, A
    Dormishian, F
    Domingo, R
    Ellis, MC
    Fullan, A
    Hinton, LM
    Jones, NL
    Kimmel, BE
    Kronmal, GS
    Lauer, P
    Lee, VK
    Loeb, DB
    Mapa, FA
    McClelland, E
    Meyer, NC
    Mintier, GA
    Moeller, N
    Moore, T
    Morikang, E
    Prass, CE
    Quintana, L
    Starnes, SM
    Schatzman, RC
    Brunke, KJ
    Drayna, DT
    Risch, NJ
    Bacon, BR
    Wolff, RK
    [J]. NATURE GENETICS, 1996, 13 (04) : 399 - 408
  • [24] The hemochromatosis founder mutation in HLA-H disrupts beta(2)-microglobulin interaction and cell surface expression
    Feder, JN
    Tsuchihashi, Z
    Irrinki, A
    Lee, VK
    Mapa, FA
    Morikang, E
    Prass, CE
    Starnes, SM
    Wolff, RK
    Parkkila, S
    Sly, WS
    Schatzman, RC
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (22) : 14025 - 14028
  • [25] PERSPECTIVES IN IRON-METABOLISM
    FINCH, CA
    HUEBERS, H
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1982, 306 (25) : 1520 - 1528
  • [26] INTESTINAL-ABSORPTION OF ZINC - COMPETITIVE INTERACTIONS WITH IRON, COBALT, AND COPPER IN MICE WITH SEX-LINKED ANEMIA (SLA)
    FLANAGAN, PR
    HAIST, J
    MACKENZIE, I
    VALBERG, LS
    [J]. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1984, 62 (09) : 1124 - 1128
  • [27] Fleming MD, 1997, NAT GENET, V16, P383, DOI 10.1038/ng0897-383
  • [28] Nramp2 is mutated in the anemic Belgrade (b) rat:: Evidence of a role for Nramp2 in endosomal iron transport
    Fleming, MD
    Romano, MA
    Su, MA
    Garrick, LM
    Garrick, MD
    Andrews, NC
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (03) : 1148 - 1153
  • [29] Iron supplementation moderates but does not cure the Belgrade anemia
    Garrick, M
    Scott, D
    Walpole, S
    Finkelstein, E
    Whitbred, J
    Chopra, S
    Trivikram, L
    Mayes, D
    Rhodes, D
    Cabbagestalk, K
    Oklu, R
    Sadiq, A
    Mascia, B
    Hoke, J
    Garrick, L
    [J]. BIOMETALS, 1997, 10 (02) : 65 - 76
  • [30] GARRICK MD, 1993, J BIOL CHEM, V268, P14867