Laparoscopic partial hepatectomy in the rat:: A new resectional technique

被引:16
作者
Krähenbühl, L [1 ]
Feodorovici, M [1 ]
Renzulli, P [1 ]
Schäfer, M [1 ]
Abou-Shady, M [1 ]
Baer, HU [1 ]
机构
[1] Univ Bern, Inselspital, Dept Visceral & Transplantat Surg, CH-3010 Bern, Switzerland
关键词
liver resection; laparoscopic surgery; CO2; pneumoperitoneum; gasless laparoscopy;
D O I
10.1159/000018607
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: Rats are widely used For basic research in laparoscopic surgery. We have developed a new technique of laparoscopic partial hepatectomy in the rat. Methods: 40 American Cancer Institute rats were randomized into 3 groups. Group A (n = 14) underwent laparoscopic liver resection using a CO2 pneumoperitoneum. Group B (n = 14) was operated on with a gasless laparoscopic technique using a lifting device. A control group C (n = 12) underwent conventional open liver resection. In each group half of the animals underwent single lobectomy and the other half bilobectomy. Results: The liver resection was performed successfully in all 40 rats. No conversion to open surgery was necessary. No mortality or morbidity was observed. Conclusions: This new technique of laparoscopic partial hepatectomy proved to be feasible and safe. It is the first description of a laparoscopic hepatic resection in the rat that could prove valuable in further investigations of liver physiology and pathology.
引用
收藏
页码:140 / 144
页数:5
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