Drug therapy: Antithyroid drugs

被引：769

作者：

Cooper, DS ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Sinai Hosp Baltimore, Div Endocrinol, Baltimore, MD 21215 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2005年 / 352卷 / 09期

关键词：

D O I：

10.1056/NEJMra042972

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Six decades after their introduction, antithyroid drugs continue to be important in the management of hyperthyroidism. Patients with Graves' disease, who have an approximately 40 to 50 percent chance of remission after 12 to 18 months of therapy, are the best candidates. Antithyroid drugs are deceptively easy to use, but because of the variability in the response of patients and the potentially serious side effects, all practitioners who prescribe the drugs need to have a working knowledge of their complex pharmacology.

引用

页码：905 / 917

页数：13

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