Dynamics of behavioral risk factors for HIV/AIDS:: a 6-year prospective study of injection drug users

被引:25
作者
Celentano, DD [1 ]
Muñoz, A [1 ]
Cohn, S [1 ]
Vlahov, D [1 ]
机构
[1] Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA
关键词
HIV; injection drug users; risk reduction; epidemiology; time-trends;
D O I
10.1016/S0376-8716(00)00154-X
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
This prospective study of 2960 injection drug users investigated the dynamic nature of HIV behavioral risk factors between 1988 and 1994. Behavioral risks were assessed semi-annually. Robust regression models of time-dependent covariates were used to identify longitudinal predictors of behavior change. Maintenance of risky behaviors varied over time, with risk reduction seen more among HIV infected participants than among HIV seronegatives. Those at highest risk for HIV transmission were least likely to cease engaging in these behaviors. Interventions staged according to risk behaviors, targeting incremental risk reduction rather than only promoting abstinence, may be more successful in reducing HIV transmission among drug injectors. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:315 / 322
页数:8
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