A magnetically controlled wireless optical oxygen sensor for intraocular measurements

被引：66

作者：

Ergeneman, Olgac ^{[1
]}

Dogangil, Gorkem ^{[1
]}

Kummer, Michael P. ^{[1
]}

Abbott, Jake J. ^{[1
]}

Nazeeruddin, Mohammad K. ^{[2
]}

Nelson, Bradley J. ^{[1
]}

机构：

[1] ETH, Inst Robot & Intelligent Syst, CH-8092 Zurich, Switzerland

[2] Ecole Polytech Fed Lausanne, Lab Photon & Interface, CH-1015 Lausanne, Switzerland

来源：

IEEE SENSORS JOURNAL | 2008年 / 8卷 / 1-2期

关键词：

in vivo; intraocular; iridium complex; luminescence quenching; magnetic steering; oxygen sensor; sensing;

D O I：

10.1109/JSEN.2007.912552

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

The influence of oxygen on various ophthalmological complications is not completely understood and intraocular oxygen measurements are essential for better diagnosis and treatment. A magnetically controlled wireless sensor device is proposed for minimally invasive intraocular oxygen concentration measurements. This device will make it possible to make measurements at locations that are currently too invasive for human intervention by integrating a luminescence optical sensor and a magnetic steering system. The sensor works based on quenching of luminescence in the presence of oxygen. A novel iridium phosphorescent complex is designed and synthesized for this system. A frequency-domain lifetime measurement approach is employed because of the intrinsic nature of the lifetime of luminescence. Experimental results of the oxygen sensor together with magnetic and hydrodynamic characterization of the sensor platform are presented to demonstrate the concept. In order to use this sensor for in vivo intraocular applications, the size of the sensor must be reduced, which will require an improved signal-to-noise ratio.

引用

页码：29 / 37

页数：9

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