Hodgsonox, a new class of sesquiterpene from the liverwort Lepidolaena hodgsoniae.: Isolation directed by insecticidal activity

被引:19
作者
Ainge, GD
Gerard, PJ
Hinkley, SFR
Lorimer, SD
Weavers, RT
机构
[1] Univ Otago, Dept Chem, Plant Extracts Res Unit, New Zealand Inst Crop & Food Res, Dunedin, New Zealand
[2] Ruakura Agr Res Ctr, AgRes, Hamilton, New Zealand
关键词
D O I
10.1021/jo0017685
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Hodgsonox (1), a new insecticidal sesquiterpene, has been isolated from the New Zealand liverwort Lepidolaena hodgsoniae. The structure was elucidated on the basis of 2D NMR analysis of 1 and a synthetic epoxide derivative (2). Hodgsonox represents a new class of sesquiterpene with a cyclopenta[5, 1-c]pyran ring system fused to an oxirane ring. The combination of a mono- and a 1,1 disubstituted double bond flanking the oxygenated carbon of a the pyran ring is a unique structural feature. Hodgsonox is toxic to larvae of the blowfly Lucilia cuprina.
引用
收藏
页码:2818 / 2821
页数:4
相关论文
共 12 条
[11]   11-oxygenated cytotoxic 8,9-secokauranes from a New Zealand liverwort, Lepidolaena taylorii [J].
Perry, NB ;
Burgess, EJ ;
Baek, SH ;
Weavers, RT ;
Geis, W ;
Mauer, AB .
PHYTOCHEMISTRY, 1999, 50 (03) :423-433
[12]  
ROMANUK M, 1960, COLLECT CZECH CHEM C, V25, P2540