Niche regulation of muscle satellite cell self-renewal and differentiation

被引：359

作者：

Kuang, Shihuan ^{[1
]}

Gillespie, Mark A. ^{[1
,2
]}

Rudnicki, Michael A. ^{[1
,2
]}

机构：

[1] Sprott Ctr Stem Cell Res, Ottawa Hlth Res Inst, Regenerat Med Program, Ottawa, ON K1H 8L6, Canada

[2] Univ Ottawa, Fac Med, Dept Cell & Mol Med, Ottawa, ON K1H 8M5, Canada

来源：

CELL STEM CELL | 2008年 / 2卷 / 01期

关键词：

D O I：

10.1016/j.stem.2007.12.012

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Muscle satellite cells have been shown to be a heterogeneous population of committed myogenic progenitors and noncommitted stem cells. This hierarchical composition of differentiating progenitors and self-renewable stem cells assures the extraordinary regenerative capacity of skeletal muscles. Recent studies have revealed a role for asymmetric division in satellite cell maintenance and offer novel insights into the regulation of satellite cell function by the niche. A thorough understanding of the molecular regulation and cell fate determination of satellite cells and other potential stem cells resident in muscle is essential for successful stem cell-based therapies to treat muscular diseases.

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页码：22 / 31

页数：10

相关论文

共 99 条

[1] Expression of CD34 and Myf5 defines the majority of quiescent adult skeletal muscle satellite cells [J].

Beauchamp, JR ;

Heslop, L ;

Yu, DSW ;

Tajbakhsh, S ;

Kelly, RG ;

Wernig, A ;

Buckingham, ME ;

Partridge, TA ;

Zammit, PS .

JOURNAL OF CELL BIOLOGY, 2000, 151 (06) :1221-1233

[2] Restoration of human dystrophin following transplantation of exon-skipping-engineered DMD patient stem cells into dystrophic mice [J].

Benchaouir, Rachid ;

Meregalli, Mirella ;

Farini, Andrea ;

D'Antona, Giuseppe ;

Belicchi, Marzia ;

Goyenvalle, Aurelie ;

Battistelli, Maurizio ;

Bresolin, Nereo ;

Bottinelli, Roberto ;

Garcia, Luis ;

Torrente, Yvan .

CELL STEM CELL, 2007, 1 (06) :646-657

[3] REGENERATION OF SINGLE SKELETAL-MUSCLE FIBERS INVITRO [J].

BISCHOFF, R .

ANATOMICAL RECORD, 1975, 182 (02) :215-235

[4] A temporal switch from Notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis [J].

Brack, Andrew S. ;

Conboy, Irina M. ;

Conboy, Michael J. ;

Shen, Jeanne ;

Rando, Thomas A. .

CELL STEM CELL, 2008, 2 (01) :50-59

[5] Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis [J].

Brack, Andrew S. ;

Conboy, Michael J. ;

Roy, Sudeep ;

Lee, Mark ;

Kuo, Calvin J. ;

Keller, Charles ;

Rando, Thomas A. .

SCIENCE, 2007, 317 (5839) :807-810

[6] The α7β1 integrin in muscle development and disease [J].

Burkin, DJ ;

Kaufman, SJ .

CELL AND TISSUE RESEARCH, 1999, 296 (01) :183-190

[7] MUTATION SELECTION AND NATURAL-HISTORY OF CANCER [J].

CAIRNS, J .

NATURE, 1975, 255 (5505) :197-200

[8]

CARLSON BM, 1989, AM J PHYSIOL, V256, pC1262

[9] inscuteable and numb mediate asymmetric muscle progenitor cell divisions during Drosophila myogenesis [J].

Carmena, A ;

Murugasu-Oei, B ;

Menon, D ;

Jiménez, F ;

Chia, W .

GENES & DEVELOPMENT, 1998, 12 (03) :304-315

[10] Cellular and molecular regulation of muscle regeneration [J].

Chargé, SBP ;

Rudnicki, MA .

PHYSIOLOGICAL REVIEWS, 2004, 84 (01) :209-238

← 1 2 3 4 5 6 7 8 9 10 →