Demonstration of the difference in binding affinity between the two binding sites of the ristocetin A asymmetric dimer

被引：9

作者：

Batta, G ^{[1
]}

Cristofaro, MF ^{[1
]}

Sharman, GJ ^{[1
]}

Williams, DH ^{[1
]}

机构：

[1] CAMBRIDGE CTR MOLEC RECOGNIT,DEPT CHEM,CAMBRIDGE CB2 1EW,ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 01期

关键词：

D O I：

10.1039/cc9960000101

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The titration of C-13 labelled N-acetyl-D-ala-D-ala with the glycopeptide antibiotics ristocetin A and eremomycin, monitored by C-13 NMR spectroscopy, demonstrates that the two distinct binding sites of the ristocetin A asymmetric dimer have different affinities, whereas those of eremomycin show no detectable difference.

引用

页码：101 / 103

页数：3

共 7 条

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