Synthesis of the C1-C6 subunit of discodermolide from furan

被引：18

作者：

Arjona, O ^{[1
]}

Menchaca, R ^{[1
]}

Plumet, J ^{[1
]}

机构：

[1] Univ Complutense, Fac Quim, Dept Quim Organ 1, E-28040 Madrid, Spain

来源：

TETRAHEDRON | 2001年 / 57卷 / 31期

关键词：

discodermolide; polypropionates; 7-oxanorbornene derivatives;

D O I：

10.1016/S0040-4020(01)00622-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the C-1-C-6 subunit of the potent antitumor agent discodermolide has been performed using 7-oxanorbornene derivatives, derived from furan, as key intermediates to control the stereochemistry of the incoming functional groups. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：6751 / 6755

页数：5