Characterization of surgical aerosols by the compact single-particle mass spectrometer LAMPAS 3

被引：9

作者：

Hinz, K. -P. ^{[1
]}

Gelhausen, E. ^{[1
]}

Schaefer, K. -C. ^{[1
]}

Takats, Z. ^{[1
]}

Spengler, B. ^{[1
]}

机构：

[1] Univ Giessen, Inst Inorgan & Analyt Chem, D-35392 Giessen, Germany

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2011年 / 401卷 / 10期

关键词：

Mass spectrometry; Single-particle analysis; In situ tissue analysis; Surgical aerosols; AIRBORNE PARTICLES; LASER-DESORPTION/IONIZATION; BIOLOGICAL TISSUES; IN-SITU; IDENTIFICATION; IONS;

D O I：

10.1007/s00216-011-5465-6

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

A new method is presented using an optical particle counter and the compact mobile laser mass spectrometer LAMPAS 3 for in situ analysis of single particles generated by electrosurgical dissection of biological tissues. The instrumental performance is demonstrated for analysing aerosol particles formed during rapid thermal evaporation of porcine liver and porcine kidney tissues. Particle number concentrations of up to 5,000 particles per cubic centimetre were detected during surgical dissection. Chemical analysis of tissue particles was performed by bipolar time-of-flight mass spectrometry. The application of an online mass spectrometric particle analysis for surgical aerosols is reported here for the first time.

引用

页码：3165 / 3172

页数：8

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