Variations in maternal behaviour are associated with differences in oxytocin receptor levels in the rat

被引：354

作者：

Francis, DD ^{[1
]}

Champagne, FC ^{[1
]}

Meaney, MJ ^{[1
]}

机构：

[1] McGill Univ, Douglas Hosp, Res Ctr, Dev Neuroendocrinol Lab, Verdun, PQ H4H 1R3, Canada

来源：

JOURNAL OF NEUROENDOCRINOLOGY | 2000年 / 12卷 / 12期

关键词：

maternal behaviour; oxytocin receptors; fear; lactation; rat;

D O I：

10.1046/j.1365-2826.2000.00599.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Female Long-Evans rats exhibit stable individual differences in maternal behaviours such as pup licking/grooming and arched-back nursing posture (LG-ABN). These variations in maternal behaviour are accompanied by differences in lactation-induced increases in oxytocin receptor levels in brain regions known to mediate the expression of maternal care in this species (i.e. the bed nucleus of the stria terminalis, the medial preoptic area and the lateral septum). Oxytocin receptor levels in the central nucleus of the amygdala were significantly higher in high compared to low LG-ABN females regardless of reproductive status. These findings suggest that individual differences in maternal behaviour may be directly related to variations in oxytocin receptor expression.

引用

页码：1145 / 1148

页数：4

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