Hepatitis C virus infection: when silence is deception

被引：88

作者：

Racanelli, V ^{[1
]}

Rehermann, B ^{[1
]}

机构：

[1] NIDDK, Liver Dis Sect, NIH, Bethesda, MD 20892 USA

来源：

TRENDS IN IMMUNOLOGY | 2003年 / 24卷 / 08期

关键词：

D O I：

10.1016/S1471-4906(03)00178-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Hepatitis C virus (HCV) uses complex and unique mechanisms to prevent, evade or subvert innate and adaptive immune responses and to establish persistent infection and chronic hepatitis. Recently developed experimental systems have significantly facilitated the analysis of HCV replication, virus-host interaction and pathogenesis of chronic hepatitis and have provided new insights into the mechanisms of HCV clearance and persistence.

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收藏

页码：456 / 464

页数：9

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共 75 条

[1] Hepatitis C virus and other Flaviviridae viruses enter cells via low density lipoprotein receptor [J].

Agnello, V ;

Abel, G ;

Elfahal, M ;

Knight, GB ;

Zhang, QX .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (22) :12766-12771

[2] Characterization of low- and very-low-density hepatitis C virus RNA-containing particles [J].

André, P ;

Komurian-Pradel, F ;

Deforges, S ;

Perret, M ;

Berland, JL ;

Sodoyer, M ;

Pol, S ;

Bréchot, C ;

Paranhos-Baccalà, G ;

Lotteau, V .

JOURNAL OF VIROLOGY, 2002, 76 (14) :6919-6928

[3] Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections [J].

Appay, V ;

Dunbar, PR ;

Callan, M ;

Klenerman, P ;

Gillespie, GMA ;

Papagno, L ;

Ogg, GS ;

King, A ;

Lechner, F ;

Spina, CA ;

Little, S ;

Havlir, DV ;

Richman, DD ;

Gruener, N ;

Pape, G ;

Waters, A ;

Easterbrook, P ;

Salio, M ;

Cerundolo, V ;

McMichael, AJ ;

Rowland-Jones, SL .

NATURE MEDICINE, 2002, 8 (04) :379-385

[4] HIV-specific CD8+ T cells produce antiviral cytokines but are impaired in cytolytic function [J].

Appay, V ;

Nixon, DF ;

Donahoe, SM ;

Gillespie, GMA ;

Dong, T ;

King, A ;

Ogg, GS ;

Spiegel, HML ;

Conlon, C ;

Spina, CA ;

Havlir, DV ;

Richman, DD ;

Waters, A ;

Easterbrook, P ;

McMichael, AJ ;

Rowland-Jones, SL .

JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 192 (01) :63-75

[5] Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection [J].

Bain, C ;

Fatmi, A ;

Zoulim, F ;

Zarski, JP ;

Trépo, C ;

Inchauspé, G .

GASTROENTEROLOGY, 2001, 120 (02) :512-524

[6] Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes [J].

Bartosch, B ;

Dubuisson, J ;

Cosset, FL .

JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 197 (05) :633-642

[7] Protective immune response to hepatitis C virus in chimpanzees rechallenged following clearance of primary infection [J].

Bassett, SE ;

Guerra, B ;

Brasky, K ;

Miskovsky, E ;

Houghton, M ;

Klimpel, GR ;

Lanford, RE .

HEPATOLOGY, 2001, 33 (06) :1479-1487

[8] Hepatitis C virus structural proteins assemble into viruslike particles in insect cells [J].

Baumert, TF ;

Ito, S ;

Wong, DT ;

Liang, TJ .

JOURNAL OF VIROLOGY, 1998, 72 (05) :3827-3836

[9] DNA microarray analysis of chimpanzee liver during acute resolving hepatitis C virus infection [J].

Bigger, CB ;

Brasky, KM ;

Lanford, RE .

JOURNAL OF VIROLOGY, 2001, 75 (15) :7059-7066

[10] Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication [J].

Blight, KJ ;

McKeating, JA ;

Rice, CM .

JOURNAL OF VIROLOGY, 2002, 76 (24) :13001-13014

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