International expert panel on the use of primary (Preoperative) systemic treatment of operable breast cancer: Review and recommendations

被引:255
作者
Kaufmann, M
von Minckwitz, G
Smith, R
Valero, V
Gianni, L
Eiermann, W
Howell, A
Costa, SD
Beuzeboc, P
Untch, M
Blohmer, JU
Sinn, HP
Sittek, R
Souchon, R
Tulusan, AH
Volm, T
Senn, HJ
机构
[1] Goethe Univ Frankfurt, Klin Gynakol & Geburtshilfe, D-60590 Frankfurt, Germany
[2] Univ Grosshadern, Res Cross Gynecol Hosp, Munich, Germany
[3] Charite Hosp, Berlin, Germany
[4] Heidelberg Univ, Heidelberg, Germany
[5] Gen Hosp, Hagen, Germany
[6] Gen Hosp, Bayreuth, Germany
[7] Univ Hosp, Ulm, Germany
[8] Natl Surg Adjuvant Breast & Bowel Project, Pittsburgh, PA USA
[9] Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA
[10] Natl Canc Inst, I-20133 Milan, Italy
[11] Christie Hosp NHS Trust, Manchester, Lancs, England
[12] Ctr Tumor Prevent, St Gallen, Switzerland
[13] Inst Curie, Paris, France
关键词
D O I
10.1200/JCO.2003.01.136
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Primary systemic therapy (PST) represents the standard of care in patients with locally advanced breast cancer. In addition, there is increasing information on PST in operable breast disease that supports the use of PST in routine practice. However, current regimens and techniques vary. To address this concern, a group of representatives from breast cancer clinical research groups in France, Germany, Italy, the United Kingdom, and the United States reviewed all available data on prospective randomized trials in this setting. Recommendations are made regarding terminology, indications, regimen, diagnosis before treatment, monitoring of efficacy, tumor localization, surgery, pathologic evaluation, and postoperative treatment. (C) 2003 by American Society of Clinical Oncology.
引用
收藏
页码:2600 / 2608
页数:9
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