Statics and dynamics of single DNA molecules confined in nanochannels

被引：459

作者：

Reisner, W ^{[1
]}

Morton, KJ

Riehn, R

Wang, YM

Yu, ZN

Rosen, M

Sturm, JC

Chou, SY

Frey, E

Austin, RH

机构：

[1] Princeton Univ, Dept Phys, Princeton, NJ 08544 USA

[2] Princeton Univ, Dept Elect Engn, Princeton, NJ 08544 USA

[3] Stanford Univ, Dept Phys, Stanford, CA 94309 USA

[4] Univ Munich, Dept Phys, Arnold Sommerfeld Ctr, D-80333 Munich, Germany

来源：

PHYSICAL REVIEW LETTERS | 2005年 / 94卷 / 19期

关键词：

D O I：

10.1103/PhysRevLett.94.196101

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The successful design of nanofluidic devices for the manipulation of biopolymers requires an understanding of how the predictions of soft condensed matter physics scale with device dimensions. Here we present measurements of DNA extended in nanochannels and show that below a critical width roughly twice the persistence length there is a crossover in the polymer physics.

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页数：4

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