Obesity and weight loss in polycystic ovary syndrome

被引：60

作者：

Hoeger, K ^{[1
]}

机构：

[1] Univ Rochester, Sch Med & Dent, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Rochester, NY 14642 USA

来源：

OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA | 2001年 / 28卷 / 01期

关键词：

D O I：

10.1016/S0889-8545(05)70187-X

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Polycystic ovary syndrome (PCOS) and obesity are common and complicated disorders that are influenced by genetic and environmental factors. Obesity is a prominent feature of PCOS; at least 50% of patients with PCOS are obese. Obesity appears to exert and additive, synergistic effect on the manifestations of PCOS, independently impacting insulin sensitivity, risk for diabetes, and adverse cardiovascular profile. There is evidence for the benefit of weight reduction in the management of PCOS in the obese patient. Weight loss remains a primary intervention in treatment of this disorder.

引用

页码：85 / +

页数：15

共 47 条

[21] RESTORED INSULIN SENSITIVITY BUT PERSISTENTLY INCREASED EARLY INSULIN-SECRETION AFTER WEIGHT-LOSS IN OBESE WOMEN WITH POLYCYSTIC-OVARY-SYNDROME
HOLTE, J
BERGH, T
BERNE, C
WIDE, L
LITHELL, H
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1995, 80 (09) : 2586 - 2593
[22] Restoration of reproductive potential by lifestyle modification in obese polycystic ovary syndrome: Role of insulin sensitivity and luteinizing hormone
Huber-Buchholz, MM
Carey, DGP
Norman, RJ
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (04) : 1470 - 1474
[23] 17 alpha-hydroxyprogesterone responses to leuprolide and serum androgens in obese women with and without polycystic ovary syndrome after dietary weight loss
Jakubowicz, DJ
Nestler, JE
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (02) : 556 - 560
[24] IMPROVEMENT IN ENDOCRINE AND OVARIAN-FUNCTION DURING DIETARY-TREATMENT OF OBESE WOMEN WITH POLYCYSTIC-OVARY-SYNDROME
KIDDY, DS
HAMILTONFAIRLEY, D
BUSH, A
SHORT, F
ANYAOKU, V
REED, MJ
FRANKS, S
[J]. CLINICAL ENDOCRINOLOGY, 1992, 36 (01) : 105 - 111
[25] DIFFERENCES IN CLINICAL AND ENDOCRINE FEATURES BETWEEN OBESE AND NON-OBESE SUBJECTS WITH POLYCYSTIC OVARY SYNDROME - AN ANALYSIS OF 263 CONSECUTIVE CASES
KIDDY, DS
SHARP, PS
WHITE, DM
SCANLON, MF
MASON, HD
BRAY, CS
POLSON, DW
REED, MJ
FRANKS, S
[J]. CLINICAL ENDOCRINOLOGY, 1990, 32 (02) : 213 - 220
[26] RELATION OF BODY-FAT DISTRIBUTION TO METABOLIC COMPLICATIONS OF OBESITY
KISSEBAH, AH
VYDELINGUM, N
MURRAY, R
EVANS, DJ
HARTZ, AJ
KALKHOFF, RK
ADAMS, PW
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1982, 54 (02) : 254 - 260
[27] DISTRIBUTION OF ADIPOSE-TISSUE AND RISK OF CARDIOVASCULAR-DISEASE AND DEATH - A 12 YEAR FOLLOW UP OF PARTICIPANTS IN THE POPULATION STUDY OF WOMEN IN GOTHENBURG, SWEDEN
LAPIDUS, L
BENGTSSON, C
LARSSON, B
PENNERT, K
RYBO, E
SJOSTROM, L
[J]. BMJ-BRITISH MEDICAL JOURNAL, 1984, 289 (6454): : 1257 - 1261
[28] Lefebvre P., 1997, Human Reproduction (Oxford), V12, P72
[29] Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women
Legro, RS
Kunselman, AR
Dodson, WC
Dunaif, A
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (01) : 165 - 169
[30] Legro RS, 2000, ANN NY ACAD SCI, V900, P193, DOI 10.1111/j.1749-6632.2000.tb06230.x

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