Antifungal Susceptibility Profile of Human-Pathogenic Species of Lichtheimia

被引：25

作者：

Alastruey-Izquierdo, Ana ^{[1
]}

Cuesta, Isabel ^{[1
]}

Walther, Grit ^{[2
]}

Cuenca-Estrella, Manuel ^{[1
]}

Rodriguez-Tudela, Juan Luis ^{[1
]}

机构：

[1] Inst Salud Carlos III, Ctr Nacl Microbiol, Serv Micol, Majadahonda 28220, Spain

[2] CBS KNAW Fungal Biodivers Ctr, Utrecht, Netherlands

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2010年 / 54卷 / 07期

关键词：

IN-VITRO SUSCEPTIBILITY; INOCULUM PREPARATION; SALVAGE THERAPY; POSACONAZOLE; ZYGOMYCOSIS; ASPERGILLUS; MUCORALES; STRAINS; AGENTS;

D O I：

10.1128/AAC.01270-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Forty-four isolates belonging to human pathogenic species of Lichtheimia were tested against nine antifungal agents by using the EUCAST methodology. No remarkable differences were found between the clinical species, although L. ramosa showed slightly higher MICs for all drugs. Amphotericin B was the most active drug. Among azole drugs, posaconazole had the best activity in vitro and voriconazole was inactive. Echinocandins showed activity for some isolates, suggesting a potential role in combination therapy.

引用

页码：3058 / 3060

页数：3

共 18 条

[11] Inoculum standardization for antifungal susceptibility testing of filamentous fungi pathogenic for humans [J].

Petrikkou, E ;

Rodríguez-Tudela, JL ;

Cuenca-Estrella, M ;

Gómez, A ;

Molleja, A ;

Mellado, E .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (04) :1345-1347

[12]

Pfaller MA., 2002, Reference method for broth dilution antifungal susceptibility testing of filamentous fungi: Approved standard. : NCCLS

[13] Zygomycetes in human disease [J].

Ribes, JA ;

Vanover-Sams, CL ;

Baker, DJ .

CLINICAL MICROBIOLOGY REVIEWS, 2000, 13 (02) :236-+

[14] Epidemiology and outcome of zygomycosis: A review of 929 reported cases [J].

Roden, MM ;

Zaoutis, TE ;

Buchanan, WL ;

Knudsen, TA ;

Sarkisova, TA ;

Schaufele, RL ;

Sein, M ;

Sein, T ;

Chiou, CC ;

Chu, JH ;

Kontoyiannis, DP ;

Walsh, TJ .

CLINICAL INFECTIOUS DISEASES, 2005, 41 (05) :634-653

[15] Interlaboratory evaluation of hematocytometer method of inoculum preparation for testing antifungal susceptibilities of filamentous fungi [J].

Rodriguez-Tudela, JL ;

Chryssanthou, E ;

Petrikkou, E ;

Mosquera, J ;

Denning, DW ;

Cuenca-Estrella, M .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (11) :5236-5237

[16] In vitro susceptibility of 15 strains of zygomycetes to nine antifungal agents as determined by the NCCLS M38-A microdilution method [J].

Singh, J ;

Rimek, D ;

Kappe, R .

MYCOSES, 2005, 48 (04) :246-250

[17] EUCAST Technical Note on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for conidia-forming moulds - Subcommittee on antifungal susceptibility testing (AFST) of the ESCMID European committee for antimicrobial susceptibility testing (EUCAST) [J].

Tudela, J. -L. Rodriquez ;

Donnelly, J. P. ;

Arendrup, M. C. ;

Arikan, S. ;

Barchiesi, F. ;

Bille, J. ;

Chryssanthou, E. ;

Cuenca-Estrella, M. ;

Dannaoui, E. ;

Denning, D. ;

Fegeler, W. ;

Gaustad, P. ;

Lass-Florl, C. ;

Moore, C. ;

Richardson, M. ;

Schmalreck, A. ;

Velegraki, J. A. ;

Verweij, P. .

CLINICAL MICROBIOLOGY AND INFECTION, 2008, 14 (10) :982-984

[18] Posaconazole is effective as salvage therapy in zygomycosis: A retrospective summary of 91 cases [J].

van Burik, JAH ;

Hare, RS ;

Solomon, HF ;

Corrado, ML ;

Kontoyiannis, DP .

CLINICAL INFECTIOUS DISEASES, 2006, 42 (07) :E61-E65

← 1 2 →