A better fluorescent protein for whole-body imaging

被引：31

作者：

Hoffman, Robert M. ^{[1
,2
]}

机构：

[1] AntiCanc Inc, San Diego, CA 92111 USA

[2] Univ Calif San Diego, Dept Surg, San Diego, CA 92103 USA

来源：

TRENDS IN BIOTECHNOLOGY | 2008年 / 26卷 / 01期

关键词：

D O I：

10.1016/j.tibtech.2007.10.006

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Whole-body imaging with fluorescent proteins is a powerful technology with many applications in small animals. Brighter, red-shifted proteins can make whole-body imaging more sensitive owing to reduced absorption by tissues and less scatter. A new protein called Katushka has been isolated. It is the brightest known protein with emission at wavelengths longer than 620 nm. This new protein offers the potential for non-invasive whole-body imaging of numerous cellular and molecular processes in live animals.

引用

页码：1 / 4

页数：4

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