Protein phosphatase 5 in signal transduction

被引：110

作者：

Chinkers, M ^{[1
]}

机构：

[1] Univ S Alabama, Dept Pharmacol, Mobile, AL 36688 USA

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2001年 / 12卷 / 01期

关键词：

D O I：

10.1016/S1043-2760(00)00335-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Protein phosphatase 5 (PP5) possesses unique biochemical properties, which include its tetratricopeptide repeat (TPR) targeting/regulatory domain and its ability to he activated by lipids. PP5 has been studied as a paradigm for TPR protein structure and function. Roles for PP5 in signal transduction are emerging:from cell cycle regulation and signaling by nuclear receptors, to possible regulation of membrane receptors and ion channels.

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页码：28 / 32

页数：5

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