Synthesis and application of dimeric Cinchona alkaloid phase-transfer catalysts:: α,α′-bis[O(9)-allylcinchonidinium]-o, m, or p-xylene dibromide

被引：121

作者：

Jew, SS ^{[1
]}

Jeong, BS ^{[1
]}

Yoo, MS ^{[1
]}

Huh, H ^{[1
]}

Park, HG ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Pharm, Seoul 151742, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 14期

关键词：

D O I：

10.1039/b102584h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A dimeric Cinchona alkaloid ammonium salt, alpha,alpha'-bis[ O( 9) allylcinchonidinium]- m-xylene dibromide 4, has been developed as a new efficient phase-transfer catalyst; the catalytic enantioselective alkylation of N-(diphenylmethylene)glycine tert-butyl ester using 4 provided 7 in a high enantiomeric excess (90-99% ee).

引用

页码：1244 / 1245

页数：2

共 24 条

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