Integrative Cancer Genomics (IntOGen) in Biomart

被引:13
作者
Perez-Llamas, Christian [1 ]
Gundem, Gunes [1 ]
Lopez-Bigas, Nuria [1 ]
机构
[1] Univ Pompeu Fabra, Res Unit Biomed Informat, Dept Expt & Hlth Sci, Barcelona 08003, Spain
来源
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION | 2011年
关键词
GENE-EXPRESSION; REPOSITORY;
D O I
10.1093/database/bar039
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Recently, we created IntOGen, a resource to integrate a large amount of cancer genomic data. IntOGen aims at facilitating the detection of the most recurrent alterations that drive tumorigenesis. It collates, annotates and analyzes high-throughput data about transcriptional, genomic and mutational changes taking place in tumors from different studies annotated with specific cancer types. Currently, it contains 118 studies for mRNA expression profiling and 188 studies for genomic alterations covering in total 64 different tumor topographies. In this article, we describe the Biomart portal for IntOGen. The portal provides easy access to different types of data and facilitates the bulk download of all the analysis results. Here, we describe the general features of IntOGen and give example queries to demonstrate its use. Database URL: www.intogen.org.
引用
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页数:8
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